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KMID : 0604520090350040309
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Journal of the Society of Cosmetic Scientists of Korea
2009 Volume.35 No. 4 p.309 ~ p.315
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Application as a Cosmeceutical Ingredient of Euryale ferox Seed Extract
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Choo Soo-Jin
Kim Young-Hee
Ryoo In-Ja
Xu Guang-Hua
Yoo Ik-Dong
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Abstract
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In our search for the natural cosmetic ingredients, we found that Euryale ferox seed extract exhibited the strong antioxidative activity. Five active compounds were isolated from the ethyl acetate extract through various chromatographic methods and their structures were determined by NMR and MS spectral analysis. These compounds were identified as fucosterol (1), 3-(4-hydroxy-3-methoxybenzyl)-4-[(7’R),5’-dihydroxy-3’-methoxybenzyl]tetrahydrofuran (2), resorcinol (3), pyrogallol (4) and 4-O-methylgallic acid (5).We evaluated the antioxidative, antielastase activities and melanogenesis inhibitory effects of these compounds. The values of compounds 2 ~ 5 for free radical scavenging activity were and especially compounds 4 and 5 were 6-fold more effective than ferulic acid as a positive control. And compounds 2 ~ 4 inhibited human neutrophil elastase with values of and compound 3 also inhibited melanin synthesis in B16F10 melanoma cells with an value of . These results suggest that Euryale ferox extract having a lot of various active ingredients may be useful as a natural multi-functioning agent.
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KEYWORD
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Euryale ferox, antioxidative, antielastase, melanogenesis, elastase inhibition
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